The only thing that I could think of would be the possibility that deep work could cause bruising...But then I decided to google anemia and massage and of course it came up with a FL study which said that massage was good for helping with the pain of Sickle Cell Anemia.But since I didn't think that was the information you were looking for... I decided to look a little further...And came upon this at the bodyworker.com:AnemiaDefinition: Anemia is a sign not a disease. There are many kinds and are all characterized by reduced blood red blood cell count or hemoglobinCauses: Nutritional- diet lacking in iron, amino acids or vitamin B12. Pernicious- insufficient production of red blood cells from an inability to produce a necessary factor. Hemmorrhagic- from excessive bleeding. Hemolytic- red blood cells plasma membranes rupture prematurely. Aplastic- destruction of bone marrow from toxins, radiation, or medicationsSigns/Symptoms: fatigue, unable to tolerate cold, paleness of skin, mucous membranes, gums, nail beds; shortness of breath, palpitations.Indications: May be helpfulContraindications: Contraindicated in advanced seforum.xxxes where the heart is overworked. Work with the care of a physician. Refer to appropriate health care provider. Pernicious anemia happens to run in my family, my great great grandmother had it, and 2 of my 4 sisters have been diagnosed with it as well.In addition I had a friend who died almost 2 years ago of Aplastic Anemia... that one as far as I understand it... has a high mortality rate.# Anemia - An increase in RBC;s and an increase in oxygen saturation in the blood suggests that massage is beneficial for individuals with anemia.(Information Source: Susan G. Salvo's Massage Therapy Principes & Practice, 2nd Editon)Taken from here:http://www.pensacolamassage.net/specific.html So I think it depends on the type of anemia they have. I think the best thing to do would be to speak to their doctor and get advice from him on it on a case by case basis.Anyway, hope that helps you some.