I use Quicken and spend about 10 minutes every 10 days or so to update it. Once a year, I print out my CashFlow report (2 minutes) and turn it in to my accountant. All my receipts are placed in marked envelopes as I get them, example: supplies, creditcard receipts, advertising...
My accountant does my taxes and figures my estimated taxes for the following year (paid 4 times.) He charged me about $300 last year for 2 businesses.