It also depends on what type of clubs you are looking for!
On this trip I got to try out 3 of the ones in Patong.
Tai Pan / FBI: Opens early and properly the first place to go. I wouldn't really call it a club, but more a disco like we have it the town where I comes from in Denmar. There are a lot of people who wants to party. You find it at the end of Bangla Road away from the beach.
Banana: This is more club like. Quite good. On the beach road approx. 300 yards from Bangla Road.
Tiger: I think this is properly one of the best in Patong. On Bangla Road.
Safari: Outside Patong on the way towards Karon. I've never been here myself. But people says it's very good.
But when you get there, go to MTB and ask around the Nicke or the BM's, they will know where to go.
Rgds,
SMF