Well as a long time sufferer of depression/dysthimia, even though I'm medicated, I still have difficulty finding pleasure in a lot of things. I really don't have a "pick me up".
Instead I try to find pleasure in the little things that may unexpectedly pop up....ie While running a different route last night, it took me past a farmer's field. I couldn't help but appreciate the smell of the growing crops.
Instead of happiness, I try to seek peace and quietude. That I find in running, biking, the gym, sometimes playing the guitar, and getting out on the open road in my car.
But enjoy....